bacterial and host-derived glutathione are required to activate prfa Host is for Rickettsia parkeri properly septate, avoid ubiquitylation, survive in macrophages Listeria monocytogenes regulates PrfA activity

Listeria monocytogenes regulates PrfA activity so as to increase Download Scientific Diagram Allosteric GSH binding primes PrfA for DNA binding. (A and B) Download Scientific Diagram Frontiers Metabolic host responses to infection by intracellular bacterial pathogens Listeria monocytogenes utilizes glutathione and limited inorganic sulfur compounds as sources of essential cysteine Infection and Immunity Discovery of a glutathione utilization pathway in Francisella that shows functional divergence between environmental and pathogenic species ScienceDirect Structural insights into glutathione mediated activation of the master regulator PrfA in Listeria monocytogenes Protein & Cell Springer Nature Link

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